| Vineri 24 August 2012 |
| # | Sp | Ora | Gazde | – | Oaspeti | Predictie | Cota | Casa | Rez |
| 1 |  |
19:30 | Nordsjaelland | 4-1 | Sonderjyske | 1 | 1.60 |  |
 |
| 2 | |
21:45 | Evian TG | 1-1 | Lyon | over 1,5 | 1.33 | |
|
| 3 | |
19:00 | Hertha | 2-1 | Regensburg | 1 | 1.40 | |
|
| 4 | |
21:30 | Gaz Metan | 2-0 | CSS Turnu Severin | 1 | 1.70 | |
|
| 5 | |
22:15 | Academica | 1-1 | Olhanense | under 2,5 | 1.50 | |
|